Question: why is the most heat-sensitive enzyme inactivated determining the growth and servival of the microorganism.
Answer: Refers only to essential enzymes. Inactivating the most hear-sensitive essential enzyme would stop the growth and may affect the servival of the cells.
Question: How does Prp changed into Prp-sc and cause mad cow disease?
Answer: Prp may change into Prp-sc by mutation. OR human acquired Prp-sc from food source. Prp-sc can recruit normal Prp and change its form to Prp-sc. Prp-sc aggregates to form rod-shaped polymers that can block the nutrient and energy supply of brain cells and cause mad-cow disease.
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